Week 8 NFL betting guide, odds: Top expert, model, AI, parlay, season-long, DFS fantasy picks revealed

SportsLine's team of Vegas experts and its proven model and AI PickBot get you ready for Week 8 NFL betting

The Week 8 NFL schedule has arrived and one of the most-anticipated matchups is Brock Purdy and the San Francisco 49ers hosting Dak Prescott the Dallas Cowboys. The Cowboys are coming off their bye week after suffering a lopsided 47-9 defeat at home against the Detroit Lions. The 49ers, meanwhile, limp into Sunday's showdown having lost four of their past six games and could be without receivers Deebo Samuel (questionable, wrist/pneumonia) and Brandon Aiyuk (knee, IR). The latest Week 8 NFL odds from the SportsLine Consensus list San Francisco as a 5-point favorite at home, while the over/under is 47.

Other Week 8 NFL spreads of note include the Bills vs. Seahawks (+3, 45) on Sunday and Giants vs. Steelers (-6, 36.5) on Monday Night Football, the game with the lowest over-under of the week. If you are looking for NFL picks, NFL parlays, Fantasy football rankings or NFL DFS picks for Week 8, SportsLine has you covered with its proven model, AI PickBot and team of experts. They even have one pick that returns a whopping +13000, so be sure to see what they have to say.

Self-learning AI reveals top NFL picks

SportsLine AI hit a whopping 1,862 4.5- and 5-star sports betting picks since the start of last season. Now it is back with its picks on the spread, money line and total for each Week 8 NFL game. It is backing the Patriots to cover as 7-point home underdogs against the Jets in an AFC East rivalry game with an over/under of 41, up a half-point from the opener. See AI picks for each Week 8 NFL game right here.

NFL parlay picks could generate massive payouts

SportsLine's model has returned well over $7,000 on top-rated picks since its inception, so those picks can confidently be used to fill out NFL parlay picks on betting apps. The model has built a five-team parlay for Week 8 that pays 25-1, and one of the legs is Houston (-4.5, 45) to cover at home against Indianapolis. The Texans are covering in nearly 60% of simulations, and the rest of the five-team parlay can be found here. 

Fantasy rankings to help you win your matchups

The model simulates every game 10,000 times, which has helped it produce better Fantasy rankings than human experts over the last few seasons. It has revealed its Week 8 Fantasy football positional rankings that can be used to make start-sit decisions. Ravens quarterback Lamar Jackson is its top-ranked quarterback of the week, but it also has full rankings for every position. 

The Week 8 Fantasy football waiver wire is loaded with players capable of making an impact this week and the remainder of the season. SportsLine's R.J. White breaks down the best widely available Fantasy football free agents heading into Week 8, helping you find the top options at every position rostered in fewer than 60% of leagues on CBSSports.com. See them all right here. 

NFL DFS picks from top experts 

SportsLine has a DFS optimizer that simulates every game 10,000 times and uses info from the SportsLine Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on sites like FanDuel and DraftKings. It has Lions wide receiver Amon-Ra St. Brown ranked as its top wideout, while Eagles running back Saquon Barkley is its top running back. Here are its complete Week 8 NFL DFS rankings. 

Senior Fantasy Writer Heath Cummings has locked in his projections for every Fantasy relevant quarterback, running back, wide receiver and tight end in your leagues. Not only do you get statistical projections as well as Fantasy point totals for every player in different scoring formats, but Cummings also includes DFS prices and values to help build winning DFS lineups each week. Get his Week 8 Fantasy and DFS projections right here. 

Advanced NFL model simulates every game 10,000 times 

SportsLine's model enters Week 8 of the 2024 NFL season on an incredible 12-5 betting hot streak on top-rated NFL picks this year. Longer term, it is on a 193-134 roll on top-rated NFL picks that dates back to the 2017 season and a 47-27 roll on top-rated NFL picks since Week 7 of 2022. The model has revealed picks for every game in Week 8, and one of its favorite picks is the Broncos (-11, 41) covering at home against the Panthers, which cashes well over 50% of the time. You can find the model's picks for every game here. 

NFL Vegas expert picks revealed 

SportsLine has an expansive team of NFL experts who provide quality betting advice for every game on the schedule. Insider Jason La Canfora (16-8 in last 24 NFL ATS picks) has revealed his best bets for Week 8, including the Packers (-3.5, 48.5) to cover on the road against the Jaguars in a game that opened as a pick'em. La Canfora's other best bets for this weekend can be found here.

Eric Cohen, who is 41-18 (69%) since Week 4, has exact score predictions for all 16 games. He is high on the Falcons (-1.5, 46.5) to beat the Buccaneers on the road, and is also calling for an underdog to pull off a surprising upset. Hit any of his exact score picks and you're looking at a payout well over 100-1. That pick, along with his prediction for all 15 remaining games, are available here. SportsLine's advanced computer model has also locked in its exact score predictions for every Week 8 NFL game right here.

49ers vs. Cowboys Sunday Night Football picks

The Dallas Cowboys will return from their bye week and try to bounce back from a 47-9 loss to Detroit when they head to San Francisco for this primetime matchup. SportsLine's model likes the Over (47) in that game and has also revealed its picks on the spread and money line. NFL expert Micah Roberts, who is on a 24-5 roll on 49ers games, has also locked in his best bet for SNF right here.

SportsLine's AI PickBot has locked in its player props for players like Brock Purdy, Dak Prescott and CeeDee Lamb. One of its top picks is Purdy going Over 240.5 passing yards, which has earned a 4-star rating. You can see all the top-rated NFL prop picks from the AI PickBot here.

Steelers vs. Giants Monday Night Football picks

The Pittsburgh Steelers will have a chance to extend their two-game winning streak on Monday night and keep pace with Baltimore atop the AFC North, while the Giants are looking to snap a two-game losing streak. The model likes the Over (36.5) in that game and has also revealed its picks on the spread and money line. NFL expert R.J. White, who is on a 66-35 against-the-spread roll on Steelers games, has also locked in his best bet for MNF right here.

The AI PickBot has locked in its player props for players like Daniel Jones, Malik Nabers, Russell Wilson and Najee Harris. One of its top picks is Jones staying Under 192.5 passing yards, which has earned a 4.5-star rating. You can see all the top-rated NFL prop picks from the AI PickBot here.