It has been 4 years since the start of the COVID-19 pandemic. SARS-CoV-2 has yet to be eradicated and new variants are continuously emerging.

A research team, led by Professor Zhang Jinsong from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences, revealed insights into the mechanism by which the membrane ...

Mimicking sugar structures in plants plays a crucial role in the development of effective vaccines against the stomach worm Ostertagia ostertagi. This has been demonstrated by Ruud Wilbers of Wageningen ...

Researchers at Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) in collaboration with the University of Freiburg have developed a biohybrid robot, which consists of a flour-based ...

Bacteria that live in soil and help roots fix nitrogen can boost certain plants' capacity to reproduce, according to an article published in the American Journal of Botany describing a study of this mechanism ...

We generally think of oxygen in terms of breath. Two researchers are thinking outside that box.

Researchers have discovered the neurons responsible for 'item memory,' deepening our understanding of how the brain stores and retrieves the details of 'what' happened and offering a new target for treating Alzheimer's disease.

Scientists have revealed that injury dressings found in first-aid kits can reliably be used to identify shark species involved in bite incidents by deploying medical gauze to gather DNA samples from aquatic equipment, such as surfboards.

In plants and animals, the basic packaging units of DNA, which carry genetic information, are the so-called nucleosomes. A nucleosome consists of a segment of DNA wound around eight proteins known as ...

Mother Nature is an artist, but her craft of creating animal faces requires more than a paintbrush and palette. Such highly complex shapes originate from their respective transient neural crest cells.

More than 90% of the commercially available carotenoids are synthetically produced using chemicals. To meet the increasing demand for cost-effective natural compounds in carotenoid synthesis, researchers ...

Blood vessels are responsible for the appropriate and efficient delivery of nutrients and oxygen to the whole body. To do so, they must grow and branch to reach every cell in a process called angiogenesis. ...

Magnetism occurs depending on how electrons behave. For example, the elementary particles can generate an electric current with their charge and thereby induce a magnetic field. However, magnetism can ...

A collagen hydrogel shows potential to enhance the efficacy of stem cell therapy for Parkinson's disease, according to rat model study.

A new statistical tool improves the ability to find genetic variants that cause disease. The tool combines data from genome wide association studies (GWAS) and predictions of genetic expression to limit the number of false positives and more accurately identify causal genes and variants for a disease.

Pasteurisation has always used significant amounts of heat. A new technology, however, can fulfil the same function without this heat, thus keeping a key protein intact.

Galantamine is a common medication used by people with Alzheimer's disease and other forms of dementia around the world to treat their symptoms. Unfortunately, synthesizing the active compounds in a lab ...

Researchers describe how specific gene activity could potentially enhance immune cell production. The researchers wanted to understand the mechanism of why some hematopoietic stem cells produce more immune cells, while other stem cells produce fewer. The research team pioneered new techniques for understanding the quantitative association between immune cell production and gene expression in lab mice. The scientists labeled individual stem cells with genetic 'barcodes' to track their immune cell production. They then correlated the barcode tracking with measurements of gene expression activity. They also developed innovative bioinformatics approaches to characterize their quantitative association. The scientists identified nearly 40 genes that are related to immune cell production. They discovered associations between the activity of these genes and both the quantity and variety of immune cells produced.

New research shows how important protein keeps our cell membranes in balance. Researchers have studied the structure, function and mechanisms of the protein ATP8B1, which flips lipid molecules in our cell membranes and plays a key role in bile biosynthesis. Importantly, ATP8B1 has also emerged as a genetic marker of Alzheimer's resilience. These results give new possibilities for therapeutic interventions in conditions related to bile homeostasis disorders and neurodegenerative diseases.

Four plants consumed by wild gorillas in Gabon and used by local communities in traditional medicine show antibacterial and antioxidant properties, find Leresche Even Doneilly Oyaba Yinda from the Interdisciplinary ...

An iron-binding drug that is already approved for treatment of other diseases could provide a novel way to attack ovarian tumors, according to a new study led by Weill Cornell Medicine researchers.

Scientists are developing an engineered parasite to get drugs into the brain.

This study is led by Prof. Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital).

A Ludwig Cancer Research study has identified a metabolic switch in the immune system's T cells that is essential to the generation of memory T cells-;which confer lasting immunity to previously encountered pathogens-;and a T cell subtype found in tumors that drives anti-tumor responses during immunotherapy.

An Argonne team developing materials for solid-state batteries has taken an unexpected detour to investigate tiny short-circuits known as soft-shorts. Their insights will benefit battery researchers around ...

Weill Cornell Medicine investigators discovered that unique bacteria colonize the gut shortly after birth and make the neurotransmitter serotonin to educate gut immune cells.

Researchers at University of Tsukuba have made a significant contribution to the understanding of the regeneration of skeletal muscle stem cells, shedding light on the mechanisms underlying muscle aging ...

Phosphorylated alpha-synuclein, a modified form of the protein that clumps in Parkinson’s, may play a role in normal nerve cell function.

By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

Scientists are on the verge of a cancer breakthrough after working out how the body's immune system targets cells devastated by the disease.

Through an international collaboration, scientists at St. Jude Children's Research Hospital have leveraged data science, pharmacology and structural information to conduct an atomic-level investigation ...

With atmospheric carbon dioxide at record highs, the search for clean-energy alternatives to the use of fossil fuels is growing increasingly urgent.

Scientists discovered a novel signaling pathway in liver cells, leading to a treatment for fibrosis.

Innovative new research has revealed that the activity of different versions of genes expressed in the brain is associated with the accumulation of the protein tau, which is a hallmark of Alzheimer's disease.

Lung tumors called adenocarcinomas sometimes respond to initially effective treatments by transforming into a much more aggressive small cell lung cancer (SCLC) that spreads rapidly and has few options for treatment. Researchers have developed a mouse model that illuminates this problematic process, known as histological transformation. The findings advance the understanding of how mutated genes can trigger cancer evolution and suggest targets for more effective treatments.

Indian Space Research Organisation (ISRO) scientists did a simulation on the ground before the launch and later did another round of checks of the systems in space before going ahead with the successful deployment of the lander on the dark side of the moon during the Chandrayaan-3 Mission, said its Director M. Srikanth.

A new approach for delivering miniature research tools into the interior of egg cells and embryos has been developed at the Marine Biological Laboratory (MBL), resolving a major bottleneck to using the ...

Highly reducing or oxidizing photocatalysts are a fundamental challenge in photochemistry. Only a few transition metal complexes with Earth-abundant metal ions have so far advanced to excited state oxidants, ...

Lipids are the main constituents of our cell membranes, which are formed as lipid bilayers. The distribution of lipids is far from uniform; it is asymmetric, with different lipid compositions in the outside ...

The common roundworm has helped Monash University researchers unlock new information about fertility and genes. Professor Roger Pocock of Monash University's Biomedicine Discovery Institute has led a ...

A microbial sensor that helps identify and fight bacterial infections also plays a key role in the embryonic development of blood stem cells, valuable new insight in the effort to create patient-derived blood stem cells that could eliminate the need for bone marrow transplants.

Norwegian University of Science and Technology (NTNU) researchers have developed a promising antibiotic candidate against MRSA. Behind the discovery lies a methodology that may be important in the fight ...

Researchers combined artificial intelligence and chemical biosensors to ferment the precursor of an Alzheimer's drug in bacteria.

A molecular “snapshot” of a protein can be critical to understanding its function. Scientists at Stanford and NYU have published and investigated a new structure of the protein LAG-3 which could enable the development of new cancer treatments.

Researchers have improved the nutritional value of plant-based milks through the implementation of simple pretreatment methods.

ETH Professor of Agriculture and later Federal Councilor Friedrich Traugott Wahlen, whose 125th birthday is being celebrated this year, endeavored to increase the self-sufficiency of Switzerland's food ...

Genetic loss of miR-205 in mice enhances mammary gland development and branching, challenging previous lethality findings and highlighting its onco-suppressive functions.

A team has introduced a strategy for converting carbon-nitrogen atom pairs in a frequently used ring-shaped compound into carbon-carbon atom pairs. The method has potential in the quest for active ingredients for new drugs, for example.

Our bodies are home to trillions of microbes, including bacteria, viruses, fungi, and a whole host of others. Now, Stanford scientists have discovered an entirely new class of biological entities inside us, which they’ve ominously named “Obelisks.”

A team of geneticists and computer scientists from the San Diego Zoo Wildlife Alliance, Cornell University and the University of California, Santa Cruz, has created a computer model that shows it should ...